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The HRX "Harpoon" is a weapon featured in Crackdown. This weapon is added with the "Getting' Busy" DLC pack. It fires high velocity harpoons that are very strong and can stick enemies to various objects, which is used to get the "Body Armor" Achievement via attaching 5 gang member bodies to a single vehicle using this weapon. This seems to be one of the more popular weapons in the game as once the player achieves 4 star weapon skill, the time it takes to lock onto an enemy is almost instant. Once a lock is acquired, firing the weapon will pretty much guarantee a one shot kill on any enemy, aside from high value targets.

List of Weapons in Crackdown
Agency Weapons Colby "Master" · Colby EAR50 · Colby "Limpet Charge" · MSK Lobber · HRX "Harpoon" · MZ360 "Mini-Gun" · EX1 "Proximity Charge" · VS1 "Cloaking Device"
Gang Weapons Kokov "Diktat" · Smithers "Punisher" · Dempsey SO-6 "Stub" · Dempsey 190 "Equalizer" · Harman MP-50 · Ingalls X80 SMG · Ingalls MG-60 · Harlington HMG-90 · Bastion S600 "Long Eye" · Bastion SX900 "Longshot" · Watson HE79 "Grenadier" · Watson HE99 "Hothead" · Watson HE99-X "Firefly" · Grenade · Shrapnel Grenade · Cluster Grenade